Category: Cancer Research

See recent blog posts and articles about cancer research at Massachusetts General Hospital.

Tumor RNA Within Platelets May Help Diagnose and Classify Cancer, Identify Treatment Strategies

“By combining next-generation-sequencing gene expression profiles of platelet RNA with computational algorithms we developed, we were able to detect the presence of cancer with 96 percent accuracy,” says Bakhos Tannous, PhD, of the MGH Department of Neurology, co-senior author of the Cancer Cell paper along with investigators from VU University Medical Center in Amsterdam. READ MORE

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Mass. General Study Identifies Genomic Differences Between Breast Cancers of African American and White Women

“In addition to having a higher prevalence of triple-negative breast cancers than Caucasian women – something that has been documented in previous studies – we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor […]

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Mass General Researcher Using Scholar Award to Investigate New Imaging Technique For Breast Cancer

Lawrence Wald, PhD, and his team at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital are working to advance magnetic resonance imaging (MRI) and related technologies, including magnetic particle imaging (MPI), a new method to detect small magnetic “nanoparticles” injected into the blood. Supported by an MGH Research Scholar Award, Dr. Wald and colleagues are now developing a […]

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New Polymer Gel Could Improve the Safety of Slow-Release Medications

A research team from Mass General and MIT’s Koch Institute for Integrative Cancer Research are working on a new type of polymer gel that could allow swallowed medical devices or capsules to safely act inside the body over the course of days, weeks or even months. Improving the safety of slow-release medications could open the door for devices that […]

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Mass General Research Study Suggests Active Physician Interventions Can Improve Quit Rates for Long Term Smokers

(Image Courtesy of Wikimedia Commons) A new Mass General research study suggests that physicians who take a more active role in connecting high-risk, longtime smokers with resources to help them quit can significantly improve their patients’ success at becoming smoke-free. The study found that patients who receive annual lung cancer screenings due to high-risk smoking (averaging […]

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Microfabricated Device Developed at Mass General Allows Evaluation of the Efficacy, Toxicity of Drugs Metabolized Through the Liver

A team of researchers from the Mass General Center for Engineering in Medicine (CEM) has developed a new microfabricated device that simplifies the process of testing so-called “pro-drugs” for toxic side effects. A pro-drug is one that is administered in an inactive form and then transformed into an active drug via metabolism in the liver. […]

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A New Way to Screen for Cancer That’s as Easy as Swallowing a Pill

Researchers at Massachusetts General Hospital have developed an innovative new way to capture microscopic images of the esophagus using a capsule-sized, light-based imaging tool. This new method, which is currently being tested in clinical trials, could make it possible to screen millions of patients for precursors to esophageal cancer at a fraction of the current cost.

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