The Mass General Research Institute: Transforming Medicine Through Innovation

The Mass General Research Institute was established to support, promote and guide the vast biomedical research enterprise at Massachusetts General Hospital.

Massachusetts General Hospital is home to the largest hospital-based research enterprise in the U.S., with an annual budget of $928 million in 2018. The Mass General Research Institute was established in 2015 to support, guide and promote the hospital’s research enterprise.

The Mass General Research Institute is built on a culture of excellence, compassion and groundbreaking scientific achievement. Our researchers work side-by-side with physicians—in the lab, in the clinic and at the bedside—harnessing the latest technological advancements to foster discovery at every stage.

A History of Medical Innovation

As the oldest and largest teaching hospital of Harvard Medical School, Mass General has been a leader in bridging innovative science with highly advanced clinical care for more than 200 years.

Among the medical and scientific “firsts” at Mass General are the first demonstration of ether as a general anesthetic, the first X-ray exposure produced in a hospital, the first antiseptic operating suite in the U.S., and the invention of MRI and fMRI imaging technologies. [More Facts at a Glance]

Mass General Research Today

Research at Mass General takes place in over 30 departments, centers and institutes and touches every aspect of biomedicine—from fundamental science investigating the basic building blocks of life to translational research bridging the laboratory with the hospital bed to clinical trials to test new strategies for diagnosing and treating disease.

Our research community consists of 8,500 people working everyday to improve healthcare, including:

  • 2,000 principal investigators leading research teams
  • 4,000 scientists and research staff
  • 1,500 postdoctoral research fellows
  • 1,000 administrative and support staff

Our location at the center of the Boston-Cambridge biotech cluster creates numerous opportunities to collaborate with partners from industry, venture capital, philanthropists, academia, foundations, governments, philanthropists and our community to prevent disease, make medical innovation sustainable, and find cures to improve the lives of our patients and those across the globe. 

Learn more about research at Massachusetts General Hospital:

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