Does Gout Play a Role in Preventing Alzheimer’s Disease?


Could gout—a painful form of inflammatory arthritis—play a role in preventing Alzheimer’s disease? In a large study in the United Kingdom, Mass General researchers found that patients who previously had gout had a 24% lower risk of ‪#‎Alzheimers‬ disease.

Gout is caused by high levels of uric acid in the blood, which can cause complications such as kidney stones and heart problems, but uric acid also has strong anti-oxidative properties, which can help to repair cell damage. More research is now needed to confirm that uric acid plays a role in preventing Alzheimer’s disease, and if so, to test its efficacy as a possible treatment. Dr. Hyon Choi, director of Clinical Epidemiology at Mass General, is lead author of the study.


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