Protein that Repels Immune Cells Protects Transplanted Pancreatic Islets from Rejection

A new gel-based capsule solution may hold the key to successfully transplanting insulin-producing islet cells into patients with Type 1 diabetes without the need for immunosuppressive drugs. A Mass General research study has found that by encapsulating the insulin-producing islets in gel capsules that are infused with a protein to repel key immune cells, the islet cells were protected from immune system
attack without the need for immunosuppressants. Dr. Mark Poznansky (above), director of the Vaccine and Immunotherapy Center at Mass General, led the study.


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